The primary sign of coccidia is diarrhea. It may be a mild case or could be severe. Blood and mucous may be found in the stool, especially in advanced cases.

A routine fecal test, which is almost always done at an initial puppy examination, is a good idea for any new puppy whether there are signs of diarrhea or not as many puppies commonly have the parasites. There is a medication to treat this condition called Albon. Your puppy may arrive with a supply if stool is in any way soft before leaving for his or her new home. A typical treatment course last about a week or two but it is important to realize that the medication should be given until the diarrhea is gone plus a couple of more days. Medication should be given for at least five days total. Sometimes courses as long as a month are needed.